Case Study: Paget-Schroetter Syndrome (PSS) in a 21-Year-Old Male
Start Date
23-4-2026 12:00 AM
Description
The purpose of this study is to bring awareness to Paget-Schroetter Syndrome (PSS) and improve recognition of early signs and symptoms. PSS is a rare, specific classification of upper-extremity thoracic outlet syndrome. It is primarily caused by repeated overhead motions and activities. PSS consists of compression of the axillary or subclavian veins that branch out through the arm, which leads to injury of the endothelial tissue, resulting in a deep vein thrombosis (DVT). This can lead to a multitude of problems in the arm and usually must be resolved through a surgical decompression procedure. In this study, I focused on a single case of PSS in a college-age male who had recently undergone surgery to his upper-extremity prior to the onset of his symptoms and diagnosis. Finally, I researched other cases of PSS to compare and contrast with this case and highlight any abnormalities that may be present in this case.
Research Highlights
The Problem: Paget-Schroetter Syndrome (PSS) is a form of venous Thoracic Outlet Syndrome characterized by effort-induced upper extremity deep vein thrombosis in the axillary or subclavian veins, often affecting active males aged 15–35.
The Method: This clinical case study examines the diagnostic and surgical progression of a 21-year-old male athlete over a two-year period, comparing his outcomes to two additional cases involving non-surgical management and stress-fracture-induced blockages.
Quantitative Finding: PSS accounts for 1-4% of venous thrombosis cases; the condition affects males more than females at a ratio of approximately 2:1; the subject’s rehabilitation was extended from 8 weeks to 16 weeks due to insurance constraints; full functional recovery and the removal of residual blockages were confirmed at 12-month and 24-month follow-ups.
Qualitative Finding: Effective management of PSS requires early recognition of symptoms like post-exertional swelling and cyanosis to prevent fatal complications; surgical interventions such as first-rib resection and vein grafting provide long-term relief but may require ongoing anticoagulant therapy and regular blood monitoring to manage recurrence risks.
Recommended Citation
Lara, William Cruz, "Case Study: Paget-Schroetter Syndrome (PSS) in a 21-Year-Old Male" (2026). 2026 Student Academic Showcase. 5.
https://digitalcommons.lindenwood.edu/src_2026/Posters/1/5
Case Study: Paget-Schroetter Syndrome (PSS) in a 21-Year-Old Male
The purpose of this study is to bring awareness to Paget-Schroetter Syndrome (PSS) and improve recognition of early signs and symptoms. PSS is a rare, specific classification of upper-extremity thoracic outlet syndrome. It is primarily caused by repeated overhead motions and activities. PSS consists of compression of the axillary or subclavian veins that branch out through the arm, which leads to injury of the endothelial tissue, resulting in a deep vein thrombosis (DVT). This can lead to a multitude of problems in the arm and usually must be resolved through a surgical decompression procedure. In this study, I focused on a single case of PSS in a college-age male who had recently undergone surgery to his upper-extremity prior to the onset of his symptoms and diagnosis. Finally, I researched other cases of PSS to compare and contrast with this case and highlight any abnormalities that may be present in this case.