Document Type
Article
Publication Title
iScience
Abstract
Seven healthy, physically active men (n = 3) and women (n = 4) (30.7 ± 7.5 years, 172.7 ± 8.7 cm, 70.4 ± 11.6 kg, 23.6 ± 4.1 kg/m², 49.2 ± 8.4 mL/kg/min) supplemented for 14 days with a placebo (PLA) or 1 × 10¹⁰ CFU doses of the probiotic Veillonella atypica FB0054 (FitBiomics, New York, NY). Participants had safety panels, hemodynamics, lactate, and anaerobic capacity assessed. Stool samples were collected to evaluate for metagenomic and metabolomic changes. Exhaustion times were not different between groups, whereas anaerobic capacity tended to shorten with PLA (61.14 ± 72.04 s; 95% CI: −5.49, 127.77 s, p = 0.066) with no change with VA (13.29 ± 100.13 s, 95% CI: −79.32, 105.89 s, p = 0.738). No changes in lactate, hemodynamics, or bacterial community changes were observed, whereas 14 metabolites exhibited differential expression patterns with VA supplementation. In conclusion, VA maintained exercise performance that tended to decline in PLA. Supplementation was well tolerated with no changes in safety markers or reported adverse events.
DOI
10.1016/j.isci.2023.108643
Publication Date
12-2023
Creative Commons License
This work is licensed under a Creative Commons Attribution-Share Alike 4.0 International License.
Recommended Citation
Gross, Kristen; Santiago, Marina; Krieger, Joesi M.; Hagele, Anthony M.; Zielinska, Kinga; Scheiman, Jonathan; Jäger, Ralf; Kostic, Alex; and Kerksick, Chad, "Impact of Probiotic Veillonella atypica FB0054 Supplementation on Anaerobic Capacity and Lactate" (2023). Faculty Scholarship. 585.
https://digitalcommons.lindenwood.edu/faculty-research-papers/585